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Table 1 Mean histone enrichment for the 10 histone modifications of genes according to their expression divergence between normal and cancer condition

From: The transposable element environment of human genes is associated with histone and expression changes in cancer

   Down-regulated genes Up-regulated genes
Histone modification Normal Cancer Wilcoxon paired tests p-values Normal Cancer Wilcoxon paired tests p-values
activating H3K27ac 8.05* 7.35 <2.2e-16 13.46* 9.11 <2.2e-16
H3K9ac 8.63* 5.92 <2.2e-16 7.66* 7.39 2.78e-13
H3K36me3 2.91* 2.49 <2.2e-16 2.49* 1.65 <2.2e-16
H3K4me1 5.58* 5.28 8.99e-5 6.09 6.28* <2.2e-16
H3K4me2 9.74 9.51 0.1682 8.06 11.10* <2.2e-16
H3K4me3 6.83* 5.73 0.0002763 6.65 9.42* <2.2e-16
H3K79me2 4.03* 1.92 <2.2e-16 2.97 4.46* <2.2e-16
repressing H3K27me3 1.76 5.86* <2.2e-16 3.54 3.35 0.009098
H3K9me3 2.16* 0.96 <2.2e-16 1.69* 1.40 3.46e-7
H4K20me1 1.27 1.52* 5.56e-9 0.92 2.97* <2.2e-16
  1. *Significantly more enrichment (p-value < 0.0025)