|  | Down-regulated genes | Up-regulated genes | ||||
---|---|---|---|---|---|---|---|
Histone modification | Normal | Cancer | Wilcoxon paired tests p-values | Normal | Cancer | Wilcoxon paired tests p-values | |
activating | H3K27ac | 8.05* | 7.35 | <2.2e-16 | 13.46* | 9.11 | <2.2e-16 |
H3K9ac | 8.63* | 5.92 | <2.2e-16 | 7.66* | 7.39 | 2.78e-13 | |
H3K36me3 | 2.91* | 2.49 | <2.2e-16 | 2.49* | 1.65 | <2.2e-16 | |
H3K4me1 | 5.58* | 5.28 | 8.99e-5 | 6.09 | 6.28* | <2.2e-16 | |
H3K4me2 | 9.74 | 9.51 | 0.1682 | 8.06 | 11.10* | <2.2e-16 | |
H3K4me3 | 6.83* | 5.73 | 0.0002763 | 6.65 | 9.42* | <2.2e-16 | |
H3K79me2 | 4.03* | 1.92 | <2.2e-16 | 2.97 | 4.46* | <2.2e-16 | |
repressing | H3K27me3 | 1.76 | 5.86* | <2.2e-16 | 3.54 | 3.35 | 0.009098 |
H3K9me3 | 2.16* | 0.96 | <2.2e-16 | 1.69* | 1.40 | 3.46e-7 | |
H4K20me1 | 1.27 | 1.52* | 5.56e-9 | 0.92 | 2.97* | <2.2e-16 |