Table 3 Relative importance of individual variables in multivariable models (ridge) for OS
From: AID/APOBEC-network reconstruction identifies pathways associated with survival in ovarian cancer
Clinics | Combined | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Pos. | Variables | beta | HR | STDBETA | Pos. | Variables | beta | HR | STDBETA |
1. | Peritoneal carcinomatosis | 0.83 | 2.30 | 0.38 | 1. | ID3 | 0.30 | 1.35 | 0.52 |
2. | Age | 0.02 | 1.02 | 0.27 | 2. | Peritoneal carcinomatosis | 1.05 | 2.86 | 0.48 |
3. | Histology | 0.58 | 1.79 | 0.19 | 3. | Age | 0.03 | 1.03 | 0.40 |
4. | FIGO stage | 0.48 | 1.62 | 0.18 | 4. | PTPRC (CD45) | 0.19 | 1.21 | 0.34 |
5. | Residual disease | 0.37 | 1.45 | 0.17 | 5. | AICDA | 0.14 | 1.15 | 0.33 |
6. | Grading | 0.34 | 1.41 | 0.15 | 6. | APOBEC3G | −0.19 | 0.83 | −0.31 |
AID/APOBEC | 7. | Grading | 0.53 | 1.70 | 0.23 | ||||
Pos. | Variables | beta | HR | STDBETA | 8. | Histology | 0.67 | 1.96 | 0.22 |
1. | ID3 | 0.18 | 1.19 | 0.30 | 9. | ID2 | −0.12 | 0.89 | −0.22 |
2. | AICDA | 0.09 | 1.09 | 0.21 | 10. | FIGO stage | 0.50 | 1.64 | 0.18 |
3. | APOBEC3G | −0.11 | 0.89 | −0.19 | 11. | Residual disease | 0.36 | 1.44 | 0.17 |
4. | PTPRC (CD45) | 0.08 | 1.08 | 0.14 | 12. | NUGGC | −0.08 | 0.92 | −0.16 |
5. | ESR1 | −0.06 | 0.94 | −0.11 | 13. | PAX5 | −0.06 | 0.94 | −0.16 |
6. | PRDM1 | 0.06 | 1.06 | 0.10 | 14. | ESR1 | −0.08 | 0.92 | −0.16 |
7. | APOBEC3B | 0.05 | 1.05 | 0.09 | 15. | ESR2 | 0.04 | 1.04 | 0.14 |
8. | XRCC5 (Ku80) | −0.06 | 0.95 | −0.07 | 16. | APOBEC3A | −0.07 | 0.93 | −0.14 |
9. | APOBEC3A | −0.03 | 0.97 | −0.07 | 17. | APOBEC3C | −0.10 | 0.91 | −0.11 |
10. | APOBEC3C | −0.06 | 0.95 | −0.06 | 18. | APOBEC3D | 0.06 | 1.06 | 0.09 |
11. | PAX5 | −0.02 | 0.98 | −0.06 | 19. | APOBEC3F | 0.06 | 1.06 | 0.07 |
12. | ID2 | −0.03 | 0.97 | −0.05 | 20. | XRCC6 (Ku70) | 0.05 | 1.05 | 0.06 |
13. | XRCC6 (Ku70) | 0.04 | 1.04 | 0.05 | 21. | NANOG | 0.04 | 1.04 | 0.06 |
14. | FCER2 | −0.02 | 0.98 | −0.05 | 22. | APOBEC3H | 0.03 | 1.03 | 0.06 |
15. | APOBEC3F | 0.03 | 1.03 | 0.03 | 23. | PRDM1 | 0.03 | 1.03 | 0.04 |
16. | ESR2 | 0.01 | 1.01 | 0.03 | 24. | APOBEC3B | 0.02 | 1.02 | 0.03 |
17. | APOBEC3H | −0.01 | 0.99 | −0.01 | 25. | APOBEC4 | 0.01 | 1.01 | 0.02 |
18. | APOBEC4 | 0.00 | 1.00 | 0.01 | 26. | XRCC5 (Ku80) | −0.02 | 0.98 | −0.02 |
19. | APOBEC3D | 0.00 | 1.00 | −0.01 | 27. | FCER2 | 0.00 | 1.00 | 0.00 |
20. | NUGGC | 0.00 | 1.00 | −0.01 | |||||
21. | NANOG | 0.00 | 1.00 | −0.01 | |||||