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Table 1 Differentially expressed oral vs. aboral genes

From: A transcriptional time-course analysis of oral vs. aboral whole-body regeneration in the Sea anemone Nematostella vectensis

ID

Annotation

Adjusted p-value

Concordance

Higher activity in

Hour of strongest change

In side

Level of log highest change

v1g28237

Transcription factor sp5

7.14E-07

−0.17115

Oral

Hour 24

Oral

2.9849

v1g83478

Lactose-binding lectin l-2- partial

1.66E-07

−0.12819

physa

Hour 72

Physa

2.00183

v1g130873

Homeobox protein six3 (Nv-Six3/6)

1.58E-06

−0.12477

physa

Hour 24

Physa

2.0107

v1g213735

OtxC

8.12E-11

−0.07607

physa

Hour 8

Physa

4.721525

v1g234699

Twist-related protein 2-like

2.02E-08

−0.07025

Oral

Hour 24

Oral

7.370836

v1g128302

MoxB

8.11E-07

−0.06785

Oral

Hour 24

Oral

5.729278

v1g240144

Predicted protein

1.52E-08

−0.03445

physa

Hour 8

Oral

4.599914

v1g187332

Forkhead box protein b1

4.09E-07

−0.02903

Oral

Hour 8

Oral

2.974586

v1g236657

Protein

1.72E-06

−0.01588

physa

Hour 24

Physa

2.600729

v1g19039

Transcription factor 24-like

2.55E-08

−0.00569

Oral

Hour 72

Oral

3.74859

v1g128296

Homeobox protein mox-2-like

4.21E-11

−0.00251

Oral

Hour 72

Oral

6.851678

v1g143839

dbh-like 1

1.10E-08

0.00088

physa

Hour 24

Physa

5.102618

v1g128275

Homeobox protein mox-1-like

2.02E-07

0.00604

Oral

Hour 24

Oral

4.413361

v1g158342

Protein Wnt (Nv-Wnt1)

1.73E-13

0.01381

Oral

Hour 72

Oral

5.89264

v1g209762

protein notum homolog

9.33E-08

0.01413

Oral

Hour 8

Oral

2.961176

v1g91822

Protein Wnt (Nv-WntA)

7.02E-06

0.05128

Oral

Hour 24

Oral

4.354627

v1g204932

Tryptophanase

2.68E-13

0.05226

Oral

Hour 24

Oral

4.082363

v1g209293

Protein

8.58E-08

0.06309

Oral

Hour 72

Oral

5.050021

v1g128289

Homeobox protein mox-1

1.36E-14

0.07061

Oral

Hour 24

Oral

6.652978

v1g90018

Serine threonine-protein kinase nek10

2.42E-06

0.09293

Oral

Hour 24

Oral

1.887118

v1g99612

Transcription factor sp9

4.12E-06

0.10237

Oral

Hour 24

Oral

2.906741

v1g82259

Camp-dependent protein kinase regulatory chain

2.54E-07

0.10922

physa

Hour 24

Physa

4.219632

v1g79707

Diencephalon mesencephalon homeobox protein 1(Nv-DMBXa)

4.70E-10

0.11036

Oral

Hour 72

Oral

4.284746

v1g235967

Transcription factor sox-14 (Nv-Sox1)

3.13E-06

0.11449

Oral

Hour 24

Oral

2.215064

v1g242584

Protein Wnt (Nv-Wnt2)

6.25E-14

0.12361

Oral

Hour 72

Oral

3.400295

v1g205060

Tetratricopeptide repeat protein 34-like

4.30E-09

0.12377

physa

Hour 8

Physa

2.469459

v1g211802

Glutamine-rich protein 2

1.75E-06

0.12696

physa

Hour 72

Physa

4.404417

v1g101383

A disintegrin and metalloproteinase with thrombospondin motifs 17

6.16E-08

0.13962

Oral

Hour 8

Oral

4.0445

v1g33652

NA

0

0.1429

Oral

Hour 24

Oral

4.929053

v1g25772

NA

4.83E-11

0.1469

Oral

Hour 24

Oral

5.117176

v1g194914

Protein Wnt (Nv-Wnt4)

0

0.15175

Oral

Hour 24

Oral

7.726335

v1g121336

Protein apcdd1

1.01E-06

0.15885

physa

Hour 8

Physa

2.812523

v1g228590

Cathepsin l-like

0

0.16234

Oral

Hour 24

Oral

5.303226

v1g247951

Chitin deacetylase 9 precursor

2.24E-12

0.17734

Oral

Hour 72

Oral

5.023155

v1g100430

Protein wntless homolog isoform 1

0

0.18089

Oral

Hour 72

Oral

3.727024

v1g196726

Integrin alpha-8

1.64E-11

0.19342

Oral

Hour 24

Oral

2.564167

  1. Some of the most prominently DE genes of the screen are presented sorted by their concordance correlation coefficient (CCC). The column ‘higher activity’ notes the side of regeneration in which there was a higher level of expression in most of the sampled hours. The column ‘hour of strongest change’ indicates the hour with the largest change in expression levels between hours of regeneration and notes the side of the strongest change (log2) in expression level. Wnt family genes are marked in bold. Homeobox genes are underlined