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Table 1 Summarizes the datasets described below

From: In vivo Ebola virus infection leads to a strong innate response in circulating immune cells

Study

Ref.

Tissue

Group

Platform

Num. animals

Num. samples

Timepoints (samples/timepoint)

Macaque model of intramuscular exposure to Ebola virus

[17]

PBMC

rVSV/EBOV-GP (vaccinated)

RNAseq

9

9

0, 4, 7 dpi (n = 3)

rVSV/MARV-GP (Ebola-naĂŻve)

RNAseq

9

9

0, 4, 7 dpi (n = 3)

Macaque model of aerosol exposure to Ebola virus

[19]

PBMC

EBOV

RNAseq

8

12

0 (n = 4), 1 (n = 2), 3 (n = 2), 6 (n = 2), 8 (n = 2) dpi

Microarray

14a

36a

0 (n = 18), 1 (n = 2), 3 (n = 2), 4 (n = 4), 5 (n = 4), 6 (n = 2), 7 (n = 2), 8 (n = 2) dpi

Spleen

RNAseq

19

19

0 (n = 2), 1 (n = 3), 3 (n = 3), 4 (n = 2), 5 (n = 2), 6 (n = 2), 7 (n = 3), 8 (n = 2) dpi

Adrenal gland

12

12

1 (n = 2), 3 (n = 1), 4 (n = 2), 6 (n = 1), 7 (n = 3), 8 (n = 2) dpi

Lymph node

6

6

0, 1, 3, 4, 5, 6 dpi (n = 1)

Brain

10

10

1, 3, 4, 6, 7 (n = 2)

Liver

4

4

0, 3, 5, 8 dpi (n = 1)

Pancreas

3

3

0, 4, 8 dpi (n = 1)

Mouse model of exposure to Ebola virus

[9]

Spleen

WT-EBOV

Microarray

15

15

0 (n = 2), 12 (n = 4), 24 (n = 3), 36 (n = 3), 48 (n = 3) hpi

MA-EBOV

14

14

0 (n = 2), 12 (n = 3), 24 (n = 3), 36 (n = 3), 48 (n = 3) hpi

Macaque model of aerosol exposure to Lassa and Marburg virus

[24]

PBMC

LASV

RNAseq

7

12

0 (n = 4), 3 (n = 4), 6 (n = 2), 10 (n = 2) dpi

 

9

12

0, 3, 5, 9 dpi (n = 3)

  1. a 8 of these animals (and 12 of these samples) correspond to the 8 animals (and 12 samples) that were quantified using RNA sequencing)