Secondary metabolite gene clusters in the entomopathogen fungus Metarhizium anisopliae: genome identification and patterns of expression in a cuticle infection model

Table 3 Expression profiling of the M. anisopliae cluster related to the biosynthesis of a helvolic acid compound

NCBI gene locus ID	Expression (RPKM)			Differential expression (log2-fold change)		Gene product
NCBI gene locus ID	48hC	48hI	144hI	48hCx48hI	48hIx144hI	Gene product
MANI_010527	0.54	13.59	2.67	4.51	−2.27	Cytochrome P450
MANI_010536	8.44	36.91	1.48	2.22	−4.50	Transferase family protein
MANI_010512	4.59	25.08	0.42	2.56	−5.58	FAD binding domain-containing
MANI_010537	3.03	30.78	4.47	3.42	−2.72	Transferase family protein
MANI_010532	0.00	12.57	0.91	6.73	−3.60	Cytochrome P450
MANI_010594	3.34	25.10	6.37	2.94	−1.90	3-oxoacyl-reductase 1
MANI_010495	9.06	87.20	9.34	3.44	−3.17	Squalene-hopene-cyclase
MANI_010530	11.58	48.40	11.28	2.21	−2.09	Cytochrome P450
MANI_010531	84.51	57.83	17.62	NA	−1.67	Cytochrome P450

The relative changes in expression levels were estimated at 48 h for the control condition (hC) and both 48 and 144 h for infection conditions (hI). NA Not Available, ND No Difference

ISSN: 1471-2164