Fig. 5
From: Genome-wide identification and characterisation of HOT regions in the human genome
Dynamics of HOT regions during H1 differentiation a Dynamic changes in HOT regions during the differentiation of H1 cell to its derived cells. The proportions of “gained” HOT regions (orange) and “shared” HOT regions (blue) in H1-derived cells are shown. b Boxplot showing the expression of genes associated with “gained” HOT regions in H1-derived cells and the IMR90 cell type (red) and in H1ES cells (blue), p-values were calculated by the Kolmogorov-Smirnov test. c GO analysis of genes associated with “gained” HOT regions in H1-derived cells and the IMR90 cell type using DAVID. For each cell type, top five biological processes were shown. d Boxplot showing the expression of enriched TF genes in HOT regions of H1-derived cells and the IMR90 cell type (red) and in H1ES cells (blue); p-values were calculated by the Kolmogorov-Smirnov test. See also Additional file 2: Tables S8 and S9