Fig. 1

Gene models and transcripts. In the CCDS Database [18], as of June 2016, there were 18 CREM human and 12 Crem mouse transcripts with unique splicing patterns. The common reference sequence has blocks labeled from A to U. The human gene model is at the top of the figure, followed by the sub-sequence of blocks and signals found in the mouse. The block representation and CCDS number is given for each transcript. Note that block O does not exist in the mouse gene, and block F is not in the human model, since block F is not found in any known human transcript. Of the 18 human transcripts, 15 are executable – meaning that they could be expressed –, and three are not (in red) because they use block O. The executable transcripts are further classified as found (5 of them, in black) and paired with a mouse transcript, or yet-to-be-found (10 of them, in green). All these predictions are confirmed by the controller. Since 5 mouse transcripts are correctly identified, and 12 mouse transcripts are currently known, the predictor successfully identifies 5/12, or 42 % of the mouse transcripts. As more mouse transcripts are discovered, this proportion may increase with future releases of the CCDS database