| Our ISREs n = 132 | [9] n = 574 | Random n = 574 |
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Counts | 0.644 ± 0.006 | 0.601 ± 0.008 | 0.609 ± 0.008 |
+NMD | 0.810 ± 0.006 | 0.788 ± 0.005 | 0.805 ± 0.006 |
Cons | 0.693 ± 0.006 | 0.608 ± 0.008 | 0.615 ± 0.007 |
- AUCs for absolute Ψ prediction using k-mer counts, counts plus two nonsense-mediated decay (NMD) features from [12], and conservation-weighted counts for various k-mer sets. The conservation weight of each k-mer instance is the minimum conservation over its k bases, to avoid counting non-functional k-mer instances that partially overlap functional ones. Our ISREs predict Ψ more accurately than [9]’s, which perform no better than the same number of random k-mers