Fig. 6

miR-376b promoted RPASMCs proliferation. a, RPASMCs transfected with miR-376b or control mimic were incubated with EDU solution for 4 h, and then were fixed and stained with Apollo dye (red) and DAPI (blue); b, Bar charts showing relative EdU incorporation rate in miR-376b transfected RPASMCs, n = 3, data are shown as mean ± SD. *p < 0.05 vs control mimic; c, Bar charts showing quantification of miR-376b in transfected RPASMCs. n = 3, data are shown as means ± SD, ***p < 0.001 vs control; d, Model depicting PDGF-BB promoted proliferation via regulating miR-376b-induced BMPR2 decrease