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Table 3 KEGG pathway enrichment for the acute kidney injury (AKI)-relevant gene set

From: Mining kidney toxicogenomic data by using gene co-expression modules

Pathway

Count

p-valuea

ECMb-receptor interaction

14

9.10−5

Glutathione metabolism

11

4.10−4

Cell adhesion molecules

16

0.012

Bile secretion

10

0.012

Cytosolic DNA-sensing pathway

7

0.026

Cysteine and methionine metabolism

6

0.026

p53 signaling pathway

9

0.026

RIG-Ic-like receptor signaling pathway

8

0.029

Toxoplasmosis

12

0.039

Amoebiasis

10

0.039

Focal adhesion

15

0.046

Metabolism of xenobiotics by cytochrome P450

8

0.046

  1. a p-value after Benjamini-Hochberg multi-test correction, bExtracellular matrix
  2. cRetinoic acid-inducible gene-1