Fig. 11

The differential expression of 40 DEGs in qPCR validation and the statistical analysis of the DEGs between control and CCI-779-treated groups. X-axis shows genes validated in this study, among which some genes have different gene name and symbol, including GST (LOC102179473, LOC102189581, LOC102188913), mmsB (PSIP1), bdh (BDH2), CYP 1B1 (LOC102184252), PIK3C (PIK3CD), ATGL (LIPG), FNTB (CHURC1), udk (UCK1), ndk (LOC102176263), Cyt b5R (LOC102173645), OGT (TTC5), ACH1 (STARD10), VEGF (LOC102177848), RPB1 (ODF3L2); Y-axis shows log2ratio of expression of CCI-779 treatment versus control group. The blue column represents the expression in control groups, and which value was defined as reference value (1.0). The red column represents the differential expression fold change of CCI-779 treatment versus control group. The qPCR data are expressed as the mean of triplicates, and error bars represent the standard deviation. Differences in means between control and CCI-779-treated groups determined by Student’s T test. The differential expression between each DEG in control and CCI-779-treated groups are all significantly different (p < 0.05)