Fig. 2

G-quadruplex DNA motifs associate with mitotic recombination breakpoints in the P. falciparum 3D7 genome. Box plots show the distribution of distances between recombination breakpoints and PQSs for the actual dataset (‘recombination sites’) and the null dataset (‘random sites’, n = 1 million, sampled equally across the genome). Red squares indicate means, red lines indicate medians, blue boxes indicate interquartile ranges and + indicate datapoints lying outside this range. a All breakpoints, n = 173, b All translocations, n = 99, c All indels, n = 74, d Var-associated translocations only, n = 70, e Sub-telomeric translocations only, n = 65, f Var-coding events detected in the progeny of the genetic cross only, n = 24