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Fig. 4 | BMC Genomics

Fig. 4

From: In-silico prediction and deep-DNA sequencing validation indicate phase variation in 115 Neisseria meningitidis genes

Fig. 4

Schematic representation of five VNSSRs and their sequence context. a VNSSR causing translational start site switching. b VNSSR causing the loss of a membrane-spanning domain. c VNSSR leading to the loss of the peptide C-terminal region. d VNSSR introducing changes in the peptide sequence. E) VNSSR influencing the gene promoter. f VNSSR introducing an inactivating frameshift. Dark grey arrows represent open reading frames. Black arrows marked with ATG represent in-frame ATG translational start sites. Light grey boxes represent the annotated functional domains. Stripped boxes represent VNSSRs and the related tags indicate the repeat unit motif along with the minimum and maximum number of repetitions observed in the 20 analyzed genomes. Numbers below each gene indicate the position relative to the annotated translational tart site

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