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Fig. 5 | BMC Genomics

Fig. 5

From: CASTIN: a system for comprehensive analysis of cancer-stromal interactome

Fig. 5

GO categories predominantly located in CS1, CS2 and CS3. a Top 9 GO categories predominantly located in CS1 and CS2. 10th GO category was removed because its mean signal strength was < 10. b Top 10 GO categories were predominantly located in CS1 and CS3. GO categories were sorted by the percentage of interactions located in the corresponding zones, and then sorted by the mean signal intensity of all the interactions in the GO category. The number of interactions in each zone (CS1, CS2, CS3, and CS4) is shown in ‘zones in C-S direction’ and the intensity of red color is proportional to the number of interactions. False discovery rate (q-value) is shown in ‘qvalue’. Representative genes or gene families, which appear in at least 2 GO categories and signal strength >10 for at least 1 interaction, is depicted by green boxes. ‘Mean signal’ refers to the mean signal strength of the interactions in the GO category. Four boxes in ‘zones in C-S direction’ indicate the number of interactions within each zone. Zones CS1 (top right), CS2 (bottom right), CS3 (top left), and CS4 (bottom left)

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