Fig. 4

Comparative analyses of blood conserved miRNomes amongst bat, human, pig and cow. a Cluster analysis of conserved miRNA expression levels across all 18 libraries. The raw expression counts were normalized using the quantile method. The rows were clustered using Pearson correlation method (normal distribution, P > 0.05), while the columns were clustered using Spearman correlation method (non-normal distribution, P < 0.05). b Principal component analysis (PCA) of conserved miRNA expression levels across all 18 libraries. The raw expression counts were normalized using the quantile method. The proportion of the variance is indicated for each principal component. c The differentially expressed miRNA between bat and other mammalian species. 6 DE miRNA candidates were obtained after intersecting the results