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Table 2 Pathways identified by the discordance enrichment analysis

From: Detecting discordance enrichment among a series of two-sample genome-wide expression data sets

KEGG pathway

DES

FDR

Gene PNLIP based analysis

  

Neuroactive ligand receptor interaction

>0.99

<0.01

Olfactory transduction

>0.99

<0.01

Ribosome

>0.99

<0.01

Maturity onset diabetes of the young

>0.99

<0.01

alpha-Linolenic acid metabolism

>0.99

<0.01

Glycine serine and threonine metabolism

0.98

<0.01

Steroid hormone biosynthesis

0.97

<0.01

Pentose and glucuronate interconversions

0.96

0.01

Ascorbate and aldarate metabolism

0.95

0.02

Linoleic acid metabolism

0.84

0.03

Proximal tubule bicarbonate reclamation

0.81

0.04

Gene TP53 based analysis

  

Neuroactive ligand receptor interaction

>0.99

<0.01

Olfactory transduction

>0.99

<0.01

Cardiac muscle contraction

0.89

0.04

alpha-Linolenic acid metabolism

0.85

0.07

Linoleic acid metabolism

0.80

0.09

  1. KEGG pathways with DES >0.80 are listed by decreasing order of DES with related FDR. KEGG pathways in bold font are identified by both analysis (one based on gene PNLIP and the other based on gene TP53)