Fig. 1
From: Identification of genes for engineering the male germline of Aedes aegypti and Ceratitis capitata
Importance of pre-meiotic protein expression in bipartite synthetic genetic systems. If transcription is repressed from meiosis onwards, post-meiotic translation of the transcription factor in a bipartite expression system is not adequate for expression of the target transgene (a). Expression of the transgene requires translation of the transcription factor before meiosis such that the target transgene is transcribed before transcriptional repression at meiosis (b)