Fig. 2
From: A transcriptome-based model of central memory CD4 T cell death in HIV infection
Unique TCM cell signature in HIV infection. Differential expression was defined as Log2 of fold change (Log FC) ≥ |0.5|, and Log (odds) > 0. a Pairwise comparisons of samples of CD4 T cells subpopulations from HIV+ and HIV¯ groups indicated by arrows a and d. Number of genes differentially expressed in each comparison are shown. Blue circles, controls’ samples; red squares, HIV+ patients’ samples. b Venn diagram of sets of differentially expressed genes. Each pairwise comparison is depicted by a colored oval. The number of differentially expressed genes found in more than one comparison appear in the intersections. c Heat map displaying a two-way unsupervised hierarchical clustering of 210 differentially expressed gens distinguishing HIV+ patients’ TCM cells (red bar) and controls’ TCM cells (blue bar), grouped in dendrograms. Each column represents an independent sample (biological replica) of each subpopulation, numbered 1 to 3. Each row corresponds to a differentially expressed gene