Skip to main content

Table 4 Association of COPS5 with mitochondrial pathways in normal oral tissues

From: Analysis of RNA expression of normal and cancer tissues reveals high correlation of COP9 gene expression with respiratory chain complex components

  GO and KEGG pathways Found Expected p μ
1 GO:0003954 ~ NADH dehydrogenase activity 28 4 1.1E-16 0.00184
2 GO:0006120 ~ mitochondrial electron transport 28 4 1.1E-16 0.00179
3 GO:0070469 ~ respiratory chain 42 6 1.1E-16 0.00323
4 GO:0042773 ~ ATP synthesis coupled electron transport 34 5 1.1E-16 0.00233
5 GO:0042775 ~ mitochondrial ATP synthesis coupled electron transport 34 5 1.1E-16 0.00233
6 GO:0005747 ~ mitochondrial respiratory chain complex I 27 4 1.1E-16 0.00179
7 GO:0030964 ~ NADH dehydrogenase complex 27 4 1.1E-16 0.00179
8 GO:0045271 ~ respiratory chain complex I 27 4 1.1E-16 0.00179
9 GO:0045333 ~ cellular respiration 50 8 1.1E-16 0.00437
10 GO:0044455 ~ mitochondrial membrane part 62 10 1.1E-16 0.00571
11 hsa00190 ~ oxidative phosphorylation 61 10 1.1E-16 0.00576
12 GO:0005746 ~ mitochondrial respiratory chain 36 6 1.1E-16 0.00278
13 GO:0006119 ~ oxidative phosphorylation 48 8 1.1E-16 0.00442
14 GO:0022904 ~ respiratory electron transport chain 35 6 1.1E-16 0.00273
15 GO:0016655 ~ oxidoreductase activity 28 5 1.1E-16 0.00213
16 GO:0022900 ~ electron transport chain 48 9 1.1E-16 0.00516
17 GO:0015980 ~ energy derivation by oxidation of organic compounds 57 11 1.1E-16 0.00670
18 GO:0000313 ~ organellar ribosome 24 5 1.1E-16 0.00238
19 GO:0005761 ~ mitochondrial ribosome 24 5 1.1E-16 0.00238
20 GO:0005743 ~ mitochondrial inner membrane 96 21 1.1E-16 0.01454
  1. Found: Number of genes in a particular GO or KEGG pathway found in the top 1000 r COPS5 list; Expected: number of expected genes to yield p < 0.05 appearing in 1000 genes based on the average appearance per gene (μ); μ values were calculated by the total appearance of individual pathways in the entire gene list of 20,154. P values were calculated using binomial distribution in R. Expected occurrences in a list of 1000 genes to provide p < 0.05 are listed