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Fig. 4 | BMC Genomics

Fig. 4

From: Genome-wide map of RNA degradation kinetics patterns in dendritic cells after LPS stimulation facilitates identification of primary sequence and secondary structure motifs in mRNAs

Fig. 4

Clustering of genes based on degradation patterns. a Heat map image of clusters of genes based on degradation patterns. Color codes represent rank of degradation patterns. Grey represents “NA”. b Box plot of mean gene expression levels of genes in each degradation pattern-based cluster (a). No significant differences were observed by two-sided Mann-Whitney test with Bonferroni correction (p > 0.05), except for cluster VIII compared to clusters I, II, V, VI, or VI (p < 0.05) (c) Overlaps between the degradation pattern-based clusters (a) and the gene expression-based clusters shown in Fig. 3b. Hypergeometric p values of overlaps are shown. d, e Gene Ontology term enrichment in clusters I (d) and II (e). GO terms in blue letters represent immunity-related ones. Top 10 GO terms and significant (q < 0.05) immunity-related terms are shown

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