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Fig. 3 | BMC Genomics

Fig. 3

From: ChimPipe: accurate detection of fusion genes and transcription-induced chimeras from RNA-seq data

Fig. 3

Benchmark results for 5 chimera detection programs on simulated (left) and on real (right) data. The sets of barplots on the top a, b indicate the programs’ performances at the gene pair level, while the sets of barplots at the bottom c, d indicate the programs’ performances at the junction level. For simulated data the provided measures are sensitivity (in red), precision (in blue), and F1score (in green), while for the two real datasets (Berger in red and Edgren in blue), the only provided measures are sensitivity (bars) and the total number of predictions (at the top of each bar). Here we show the results on PE76 simulated data, for the 250 simulated chimeric junctions (i.e. including read-through events). For the benchmark on real data, read-through events, i.e. junctions with a length smaller than 100kb when on the same chromosome, same strand and expected genomic order, were removed from the output of each program before the evaluation

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