Skip to main content

Table 3 Estimated optimal cutoffs based on various false positive rates (FPR) at 20, 50, and 100 per megabase and barcode depths from 500 to 3,500. The prediction equations at each FPR is also given

From: Detecting very low allele fraction variants using targeted DNA sequencing and a novel molecular barcode-aware variant caller

FPR (Mb−1) Prediction equation 500 1000 1500 2000 2500 3000 3500
20 y=14+0.012x 20 26 32 38 44 50 56
50 y=15+0.0092x 20 25 29 34 38 43 48
100 y=13+0.0088x 18 22 27 31 35 40 44