Table 5 DE genes in NFE2L2 mediated oxidative stress
Symbol | Entrez gene name | Fold change | p-value | Location | Type (s) |
|---|---|---|---|---|---|
ATM | ATM serine/threonine kinase | −1.31 | 3.95E-02 | Nucleus | kinase |
CAT | catalase | 1.67 | 7.26E-05 | Cytoplasm | enzyme |
DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 1.56 | 1.61E-02 | Cytoplasm | other |
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 1.30 | 5.86E-03 | Nucleus | transcription regulator |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | −1.45 | 1.94E-03 | Nucleus | other |
DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | −1.39 | 2.04E-02 | Cytoplasm | other |
DNAJC21 | DnaJ (Hsp40) homolog, subfamily C, member 21 | −1.97 | 3.50E-05 | Other | other |
EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 1.39 | 1.03E-02 | Cytoplasm | kinase |
FOS | FBJ murine osteosarcoma viral oncogene homolog | 4.66 | 1.06E-02 | Nucleus | transcription regulator |
HMOX1 | heme oxygenase 1 | 2.53 | 7.47E-04 | Cytoplasm | enzyme |
HRAS | Harvey rat sarcoma viral oncogene homolog | 1.43 | 1.51E-03 | Plasma Membrane | enzyme |
JUN | jun proto-oncogene | 2.45 | 2.23E-03 | Nucleus | transcription regulator |
MAP2K3 | mitogen-activated protein kinase kinase 3 | 1.33 | 1.13E-02 | Cytoplasm | kinase |
MAP2K6 | mitogen-activated protein kinase kinase 6 | −1.85 | 1.31E-02 | Cytoplasm | kinase |
MGST1 | microsomal glutathione S-transferase 1 | 1.36 | 3.58E-02 | Cytoplasm | enzyme |
MRAS | muscle RAS oncogene homolog | 1.53 | 4.77E-02 | Plasma Membrane | enzyme |
PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | −1.34 | 1.15E-02 | Cytoplasm | kinase |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | −2.66 | 1.05E-03 | Cytoplasm | kinase |
PRKCB | protein kinase C, beta | 2.28 | 2.15E-03 | Cytoplasm | kinase |
PRKCD | protein kinase C, delta | 1.41 | 2.50E-02 | Cytoplasm | kinase |
PRKCH | protein kinase C, eta | −2.95 | 7.23E-04 | Cytoplasm | kinase |
SOD3 | superoxide dismutase 3, extracellular | 2.51 | 1.48E-02 | Extracellular Space | enzyme |
TXNRD1 | thioredoxin reductase 1 | 1.74 | 7.60E-04 | Cytoplasm | enzyme |