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Table 1 GO annotations of host linear transcripts at 2 h after PH compared to GC

From: Comprehensive CircRNA expression profile and selection of key CircRNAs during priming phase of rat liver regeneration

GO

P-value

GO terms

Biological process

GO:0006801

0.000

superoxide metabolic process

GO:0007569

0.000

cell aging

GO:0042554

0.000

superoxide anion generation

GO:0072593

0.000

reactive oxygen species metabolic process

GO:0000902

2.38 × 10−7

cell morphogenesis

GO:2000573

4.12 × 10−7

positive regulation of DNA biosynthetic process

GO:0006536

3.63 × 10−6

glutamate metabolic process

GO:2000379

3.63 × 10−6

positive regulation of reactive oxygen species metabolic process

GO:0006744

2.80 × 10−5

ubiquinone biosynthetic process

GO:0043406

4.55 × 10−5

positive regulation of MAP kinase activity

Cellular component

GO:0001725

0.000158

stress fiber

GO:0005925

0.000158

focal adhesion

GO:0005789

0.000333

endoplasmic reticulum membrane

GO:0016324

0.007339

apical plasma membrane

GO:0005769

0.028955

early endosome

GO:0005829

0.031131

cytosol

GO:0005887

0.05958

integral component of plasma membrane

GO:0005615

0.061762

extracellular space

GO:0070062

0.12631

extracellular vesicular exosome

GO:0043231

0.172681

intracellular membrane-bounded organelle

Molecular function

GO:0000977

0.000

RNA polymerase II regulatory region sequence-specific DNA binding

GO:0001227

0.000

RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription

GO:0004069

0.000

L-aspartate:2-oxoglutarate aminotransferase activity

GO:0004356

0.000

glutamate-ammonia ligase activity

GO:0016175

0.000

superoxide-generating NADPH oxidase activity

GO:0004707

4.63 × 10−7

MAP kinase activity

GO:0004497

1.80 × 10−6

monooxygenase activity

GO:0070330

4.04 × 10−6

aromatase activity

GO:0004838

4.55 × 10−5

L-tyrosine:2-oxoglutarate aminotransferase activity

GO:0020037

8.29 × 10−5

heme binding