Protein Function | Gene IDs in active data set | Gene Title | Object name | Fold change | A | n | R | N | E | Ratio | z-score | p-value |
---|---|---|---|---|---|---|---|---|---|---|---|---|
TFs | IRF9 | interferon regulatory factor 9 | IRF9 | −1.7 | 7 | 102 | 60 | 26494 | 0.231 | 30.3 | 14.1 | 3.32E-09 |
STAT1 | signal transducer and activator of transcription 1, 91kDa | STAT1 | −2.6 | 22 | 102 | 575 | 26494 | 2.214 | 9.9 | 13.5 | 4.04E-16 | |
Receptors | FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | Fc gamma RII beta | −1.4 | 2 | 102 | 35 | 26494 | 0.135 | 14.8 | 5.1 | 0.0080 |
Kinases | PRKCD | protein kinase C, delta | PKC-delta | −1.7 | 8 | 102 | 386 | 26494 | 1.486 | 5.4 | 5.4 | 0.0001 |
Proteases | PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | PSMB9 | −1.7 | 3 | 102 | 38 | 26494 | 0.146 | 20.5 | 7.5 | 0.0004 |
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | PSMB8(LMP7) | −1.6 | 2 | 102 | 30 | 26494 | 0.115 | 17.3 | 5.6 | 0.0059 | |
Phosphatases | PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | SHP-1 | −1.9 | 5 | 102 | 200 | 26494 | 0.770 | 6.5 | 4.8 | 0.0010 |
Enzymes | MX1; MX2 | myxovirus (influenza virus) resistance 2 (mouse) | MxA | −3.5 ; -2.2 | 3 | 102 | 57 | 26494 | 0.219 | 13.7 | 6.0 | 0.0013 |
Others | IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | IFIT1 | −4.0 | 4 | 102 | 15 | 26494 | 0.058 | 69.3 | 16.4 | 2.74E-07 |
TOMM34 | translocase of outer mitochondrial membrane 34 | TOM34 | −1.6 | 2 | 102 | 21 | 26494 | 0.081 | 24.7 | 6.8 | 0.0029 | |
IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | RIG-G | −3.5 | 6 | 102 | 66 | 26494 | 0.254 | 23.6 | 11.4 | 2.11E-07 | |
SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | C1 inhibitor | −4.0 | 2 | 102 | 23 | 26494 | 0.089 | 22.6 | 6.4 | 0.0035 | |
NCF4 | neutrophil cytosolic factor 4, 40kDa | p40-phox | −1.8 | 2 | 102 | 23 | 26494 | 0.089 | 22.6 | 6.4 | 0.0035 | |
TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | TAP1 (PSF1) | −1.6 | 4 | 102 | 51 | 26494 | 0.196 | 20.4 | 8.6 | 4.5E-0 | |
ISG15 | ISG15 ubiquitin-like modifier | ISG15 | −4.2 | 8 | 102 | 256 | 26494 | 0.986 | 8.1 | 7.1 | 6.83E-06 |