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Fig. 9 | BMC Genomics

Fig. 9

From: Transcriptome analysis of coding and long non-coding RNAs highlights the regulatory network of cascade initiation of permanent molars in miniature pigs

Fig. 9

Overview of lincRNAs during additional molar morphogenesis. a Transcript length, exon number and expression abundance of lincRNAs were less than that of coding RNAs. b Identified lincRNAs showed low conservation when blasted to human, cow and Mus musculus. c Heatmap of the stage-specific expression of 450 putative lincRNAs during additional molar morphogenesis. d Venn diagrams of the stage-specific expression profiling of 450 differentially expressed lincRNAs show that 316 lincRNAs were identified between E50 and E60 and 358 lincRNAs between E60 and E70, and 224 lincRNAs overlapped among E50, E60 and E70. e Heatmap showing a negative correlation between lincRNAs and the neighbouring genes of the lincRNA locus between E50 and E60. f Co-Expression-Net analysis of lincRNAs and mRNAs. Left panel: genes with strong co-expression of lincRNAs (log2FC > 20 or < −20) and mRNAs (top 500 from E50 vs E60 and top 500 from E60 vs E70) from significant pathways of profiles 2 and 5. Right panel: co-expression of lincRNAs and mRNAs from significant pathways of profiles 3 and 4. Pearson coefficient > 0.999

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