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Fig. 6 | BMC Genomics

Fig. 6

From: Plasmid diversity and phylogenetic consistency in the Lyme disease agent Borrelia burgdorferi

Fig. 6

B. Burgdorferi chromosomal right end extensions. a Aligned chromosomal right end maps drawn to scale. The different colors represent very high similarity to the indicated plasmids. The black and yellow circles indicate 263 bp and 324 bp overlapping deletions, respectively, relative to the B31 chromosome. The right-end extension names and strains that carry them (in parentheses) are indicated at the right. The thin red lines with a gray circle between the L-2 and M-2 and M-3 and M-4 chromosomes indicate a large putative deletion and inversion, respectively. b. Evolutionary tree compatible with terminal replacements and rearrangements. Major rearrangements, assumed to have occurred on the chromosome and not on plasmids before they recombined with the chromosome (see text), are denoted by the small colored circles: blue, lp28-1 subtype II addition; red, lp28-1 subtype I addition; green, lp28-5 subtype I addition; black, 263 bp deletion in lp28-1 type II sequence; orange, lp28-7 addition; gray, 7 kbp inversion; purple, 12 kbp deletion; pink, addition of lp21 sequences; and yellow, enlargement of 263 bp deletion (above) to 324 bp. The right end extension names and strains that carry them (in parentheses) are indicated at the tips of the branches, and the chromosomal SNP types (see text) are given at the right. Strains 297, Sh-2-82 and CA382 were not included in the SNP analysis but fit in the SNP groups according to the facts that, like B31 in SNP group A, CA382 has a type A ospC (A. Barbour, personal communication); 297 and Sh-2-82 are both ospC type K, and 297 has lp54 and cp26 plasmids that are most closely related to the SNP group D strains (see text) [48]

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