Conserved expression of transposon-derived non-coding transcripts in primate stem cells

BMC Genomics

Table 1 TE expression conservation between human and chimpanzee iPSCs

Family	Class	Total	Human	Chimpanzee	Proportion	p-value
			expressed	expressed
MER53	DNA	5308	39	20	0.51	9.61∗10⁻²⁷
MIR1_Amn	SINE	9495	113	57	0.50	1.71∗10⁻⁷¹
AluSg7	SINE	5780	50	25	0.50	6.81∗10⁻³⁵
LTR8	LTR	2516	37	18	0.49	1.81∗10⁻²⁵
L2d	LINE	19063	135	64	0.47	2.32∗10⁻⁸⁴
Tigger4a	DNA	3242	45	21	0.47	2.41∗10⁻²⁰
MADE1	DNA	7634	86	40	0.47	7.59∗10⁻⁵¹
HERVH-int	LTR	1266	50	23	0.46	9.26∗10⁻¹⁵
MER94	DNA	4884	33	15	0.45	2.17∗10⁻²¹
L1MC1	LINE	7375	33	15	0.45	8.19∗10⁻²²
L1MC4	LINE	12920	109	49	0.45	4.17∗10⁻⁶⁴
L1MB2	LINE	4967	38	17	0.45	1.49∗10⁻²⁰
Charlie4z	DNA	5255	47	21	0.45	1.38∗10⁻²⁷
L1MB8	LINE	9006	56	25	0.45	7.32∗10⁻³⁴
L1M2	LINE	6281	56	25	0.45	4.05∗10⁻³²
OldhAT1	DNA	1897	30	13	0.43	5.22∗10⁻¹⁶
AluYk3	SINE	5421	42	18	0.43	5.12∗10⁻²⁴
MER81	DNA	3551	31	13	0.42	4.35∗10⁻¹⁸
L1MC3	LINE	6596	31	13	0.42	1.36∗10⁻¹⁷
MER1B	DNA	5060	36	15	0.42	2.05∗10⁻²⁰

Here we examine only large families (≥100) from the main repeat classes (DNA, SINE, LINE, LTR). The table is sorted by the proportion of human expressed TEs which are conserved in chimpanzee. Only repeat families with at least 30 expressed instances in human are shown

ISSN: 1471-2164