Table 5 Functionally relevant variants detected in the milk fat candidate genes considered in this study
From: Variant discovery in the sheep milk transcriptome using RNA sequencing
Varianta | Gene | Allele Freq | Effect | AA | |
|---|---|---|---|---|---|
Assaf | Churra | ||||
GCA_000298735.1:2:87107748:C:A | PLIN2 | 0.5 | 0.5 | High-Splice donor | |
GCA_000298735.1:3:20585665:C:T | LPIN1 | 0.125 | 0 | Missense-Deleterious (0) | p.Arg781Trp |
GCA_000298735.1:3:92183603:G:T | XDH | 0.5 | 0.5 | High-Splice aceptor | |
rs428221119 | XDH | 0.25 | 0 | Missense-Deleterious (0.02) | p.Leu246Phe |
rs429850918 | XDH | 0.25 | 0 | Missense-Deleterious (0) | p.Arg614Trp |
GCA_000298735.1:3:92217135:G:A | XDH | 0.5 | 0.5 | High-Splice aceptor | |
GCA_000298735.1:3:92239411: CCGCCCCTCTTCCCGGGCGCCCCCATCTTCTTTTCCA:C | XDH | 1 | 1 | Moderate-Inframe deletion | p.Pro1251_Phe1262del |
rs604791005 | FASN | 0 | 0.125 | Missense-deleterious-low_confidence (0.04) | p.Gly2312Ala |
GCA_000298735.1:26:13949071:C:T | ACSL1 | 0.5 | 0.5 | High-Splice donor | |