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Table 4 KEGG pathways identified for the downregulated genes in the high-RFI group with an FDR q-value < 0.01 from the output of the GSEA in the Jerseys

From: RNA-Seq transcriptomics and pathway analyses reveal potential regulatory genes and molecular mechanisms in high- and low-residual feed intake in Nordic dairy cattle

  Pathways name FDR q-value Core enrichment gene
1 Leukocyte transendothelial migration 0.006 NCF1, PLCG1, ICAM1, VAV1, MAPK12, MSN, PTK2, SIPA1, ITGAM, NCF4, RAP1B, VASP, PIK3CD, RHOH, PIK3R5, RAC2, RAPGEF3, ITK
CLDN14, THY1, MYL12B, CLDN4, CXCR4, ACTG1, ITGB2, CYBA, CLDN7, EZR, CYBB, CLDN1, GNAI1, NCF2, MMP2, PRKCB
2 Primary immunodeficiency 0.010 CD4, CD8A, ADA, PTPRC, JAK3, TAP1, ZAP70, CD3e, CD3D, LCK
  1. FDR q-value = adjusted p-value; core enrichment gene = subset of genes that contributes most to the enrichment result