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Table 4 KEGG pathways identified for the downregulated genes in the high-RFI group with an FDR q-value < 0.01 from the output of the GSEA in the Jerseys

From: RNA-Seq transcriptomics and pathway analyses reveal potential regulatory genes and molecular mechanisms in high- and low-residual feed intake in Nordic dairy cattle

 

Pathways name

FDR q-value

Core enrichment gene

1

Leukocyte transendothelial migration

0.006

NCF1, PLCG1, ICAM1, VAV1, MAPK12, MSN, PTK2, SIPA1, ITGAM, NCF4, RAP1B, VASP, PIK3CD, RHOH, PIK3R5, RAC2, RAPGEF3, ITK

CLDN14, THY1, MYL12B, CLDN4, CXCR4, ACTG1, ITGB2, CYBA, CLDN7, EZR, CYBB, CLDN1, GNAI1, NCF2, MMP2, PRKCB

2

Primary immunodeficiency

0.010

CD4, CD8A, ADA, PTPRC, JAK3, TAP1, ZAP70, CD3e, CD3D, LCK

  1. FDR q-value = adjusted p-value; core enrichment gene = subset of genes that contributes most to the enrichment result
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BMC Genomics

ISSN: 1471-2164

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