Table 2 The 20 most strongly down-regulated mRNAs in the liver of cows fed grape seed and grape marc meal extract (GSGME) versus control cows at 1Â week postpartum
Gene symbol | mRNA description | FCa | P-value |
|---|---|---|---|
GLCE | glucuronic acid epimerase | –1.66 | 0.036 |
TBATA | chromosome 28 open reading frame, human C10orf27 | –1.60 | 0.011 |
MANF | mesencephalic astrocyte-derived neurotrophic factor | –1.59 | 0.014 |
XBP1 | X-box binding protein 1, transcript variant 1 | –1.59 | 0.003 |
LOC618817 | olfactory receptor, family 6, subfamily B, member 2-like | –1.55 | 0.005 |
SAA4 | serum amyloid A4, constitutive | –1.54 | 0.043 |
HSPA5 | heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa) | –1.51 | 0.005 |
GADD45B | growth arrest and DNA-damage-inducible, beta | –1.51 | 0.012 |
WWC1 | WW and C2 domain containing 1, transcript variant 2 | –1.48 | 0.037 |
LOC788587 | olfactory receptor, family 4, subfamily D, member 11-like | –1.46 | 0.001 |
SOCS3 | suppressor of cytokine signaling 3 | –1.45 | 0.042 |
C15H11orf96 | chromosome 15 open reading frame, human C11orf96 | –1.44 | 0.018 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 | –1.43 | 0.012 |
SDF2L1 | stromal cell-derived factor 2-like 1 | –1.41 | 0.012 |
IRX3 | iroquois homeobox 3 | –1.40 | 0.001 |
LOC784679 | peptidylprolyl isomerase A (cyclophilin A)-like | –1.39 | 0.023 |
HYOU1 | hypoxia up-regulated 1, transcript variant 1 | –1.39 | 0.018 |
ALX3 | ALX homeobox 3 | –1.39 | 0.010 |
CFHR2 | complement factor H-related 2 | –1.39 | 0.028 |
LOC520181 | olfactory receptor 5-like | –1.39 | 0.007 |