The Krüppel-like factor 9 cistrome in mouse hippocampal neurons reveals predominant transcriptional repression via proximal promoter binding

Table 1 The top ten most up- or down-regulated genes by eight hr of forced Klf9 expression in HT22 [TR/TO-Klf9] cells (FDR-adjusted p value cutoff of .005)

Gene Symbol	Gene name	Log₂ fold change
Klf13	Krüppel-like factor 13	−1.21
Rptoros	Regulatory associated protein of MTOR, complex 1, opposite strand	−1.12
Gpr161	G Protein-coupled receptor 161	−1.11
Apc2	Adenomatosis polyposis coli 2	−1.04
Zfp704	Zinc finger protein 704	−1.02
Arhgap39	Rho GTPase Activating Protein 39	−0.96
Armc7	Armadillo Repeat Containing 7	−0.95
Mex3a	Mex-3 RNA Binding Family Member A	−0.92
Wdfy2	WD Repeat And FYVE Domain Containing 2	−0.89
Nlgn2	Neuroligin2	−0.88
Frk	Fyn-Related Src Family Tyrosine Kinase	0.43
1810043G02Rik	RIKEN cDNA 1810043G02	0.46
4930430 F08Rik	RIKEN cDNA 4930430 F08	0.47
2610301B20Rik	RIKEN cDNA 2610301B20	0.48
Tctn2	Tectonic Family Member 2	0.49
Arxes2	adipocyte-related X-chromosome expressed sequence 2	0.51
Mitd1	Microtubule Interacting and Transport Domain Containing 1	0.51
Rilpl2	Rab Interacting Lysosomal Protein-Like 2	0.51
Zfp930	Zinc-finger protein 930	0.52
Cdkn3	Cyclin-Dependent Kinase Inhibitor 3	0.56

The mRNA levels (counts) were evaluated by DESeq. Genes are ordered by log₂ fold change (lowest to highest). A complete list of differentially regulated genes is given in The mRNA levels (counts) were evaluated by DESeq. Genes are ordered by log₂ fold change (lowest to highest). A complete list of differentially regulated genes is given in Additional file 2: Table S1

ISSN: 1471-2164