Skip to main content

Table 3 Selected upregulated genes in the Malpighian tubules following cold acclimation whose putative function in relation to cold tolerance is discussed in the text

From: Effects of cold-acclimation on gene expression in Fall field cricket (Gryllus pennsylvanicus) ionoregulatory tissues

Function Description Fold change P-value Species
Apoptosis Caspase-8 2.1 1.7E-5 Zn
Programmed Cell Death Protein 2 2.4 7.0E-10 Nv
Circadian Clock 2.5 6.4E-9 Gb
Nocturnin 3.5 1.2E-23 Zn
Period 7.6 2.5E-63 Ms
Cytoskeleton Gamma-Tubulin Complex Component 6 2.2 8.6E-10 Zn
Kinesin-Like Protein Costa 2.8 2.6E-9 Zn
Protein Shroom 2.5 1.6E-9 Zn
Microtubule-Associated Protein Jupiter 2.2 1.8E-8 Zn
Ion transport Ca2+-Transporting ATPase Type 2C Member 1 2.2 1.1E-8 Zn
Solute Carrier Organic Anion Transporter Family Member 5a1 2.4 3.0E-11 Hs
Phosphorylation Inositol Polyphosphate Multikinase 2.2 2.6E-15 Zn
Serine Threonine-Protein Kinase rio3 3.4 5.4E-35 Zn
Serine Threonine-Protein Kinase pctaire-2 2.6 3.9E-14 Zn
Serine Threonine-Protein Kinase Tousled-Like 2 2.9 2.7E-11 Zn
Tyrosine-Protein Kinase Transmembrane Receptor ror1 2.5 6.6E-10 Phc
Tyrosine-Protein Phosphatase Non-Receptor Type 23 2.5 1.6E-15 Zn
Protein folding/chaperone Hsp 70 Family Member 2.0 1.0E-10 Lm
Hsp 70-binding Protein 1 3.3 2.7E-22 Zn
Repair/detoxicant/antioxidant Alkylated DNA Repair Protein Alkb-Like Protein 4 2.6 1.4E-12 Zn
Cytochrome P450 14.6 3.7E-58 Aa
Cytochrome P450 2j2 3.4 4.6E-7 Zn
Cytochrome P450 partial 6.1 9.1E-11 Zn
DNA Mismatch Repair Protein mlh1 4.2 3.9E-24 Xt
Glutathione S-Transferase Sigma 7 2.3 9.5E-9 Zn
Peroxiredoxin-6 2.1 4.0E-9 Lm
Probable Cytochrome P450 (partial) 6.2 2.6E-13 Tc
Signal transduction cAMP-Specific 3’,5’-Cyclic Isoform F Isoform X2 3.2 2.4E-30 Tc
G Kinase-Anchoring Protein 1 3.7 1.2E-28 Zn
  1. For a full list of the 999 upregulated Malpighian tubule genes, see Additional file 2: Spreadsheet S1. P-values were adjusted for false discovery rate (FDR). For each gene, the species with the highest sequence similarity via BLAST is given. Species codes: Aa (Aedes aegypti), Gb (Gryllus bimaculatus), Hs (Harpegnathos saltator), Lm (Locusta migratoria), Ms (Modicogryllus siamensis), Nv (Nasonia vitripennis), Phc (Pediculus humanus corporis), Tc (Tribolium castaneum), Xt (Xenopus tropicalis), Zn (Zootermopsis nevadensis)