Fig. 3

Canonical pathways predicted to be activated or inhibited from gene expression data. Each pathway shown is significantly enriched for our genes with a Fisher’s Exact test p-value less than 0.01 (depicted with an asterisk). Pathways were shown only if they met our criteria for significance and had a predicted activation state in at least one organ. Z-scores of 0.000 indicate pathway predictions that lack a bias in the direction of gene regulation observed in our dataset. PPAR signaling (P < 0.05) was also included