Fig. 1

Associations of the inhibitory codon pairs with synthesis and decay of mRNA and protein. a Boxplot comparing mRNA synthesis rates in the “Cramer 1” data (in log10 scale) between genes containing at least one of the 17 inhibitory codon pairs (≥1) and those without them (0). Shown on the top are the Spearman’s and Kendall’s correlation coefficients and P values (parenthesis) to assess an association of the presence (1) and absence (0) of the inhibitory codon pairs with mRNA synthesis rate. b Same as (a) but for the “Cramer 2” data. c Same as (a) but for the “Gresham” data. d Same as (a) but for the “Coller” data. e Same as (a) but for mRNA decay rate. f Same as (e) but for the “Cramer 2” data. g Same as (e) but for the “Gresham” data. h Samea s (e) but for the “Coller” data. i Same as (a) but for protein abundance per mRNA. j Same as (a) but for ribosome occupancy. k Same as (a) but for protein decay rates