Table 2 Gene Ontology Analysis - Biological Process
From: In silico pathway analysis and tissue specific cis-eQTL for colorectal cancer GWAS risk variants
GO term | Genes | Fold enrichment | p-value | FDR |
|---|---|---|---|---|
GO:0034330 ~ cell junction organization | CD9, SHROOM2, SMAD7, LAMA5, LAMC1, TGFB1 | 29.06 | 1.66 × 10−6 | 0.003 |
GO:0001763 ~ morphogenesis of a branching structure | BMP4, BMP2, LAMA5, GREM1, TGFB1, CTNNB1 | 22.38 | 6.09 × 10−6 | 0.010 |
GO:0060393 ~ regulation of pathway-restricted SMAD protein phosphorylation | BMP4, BMP2, SMAD7, TGFB1 | 64.96 | 2.75 × 10−5 | 0.044 |
GO:0002009 ~ morphogenesis of an epithelium | BMP4, BMP2, LAMA5, GREM1, CTNNB1, NKX2-3 | 16.40 | 2.79 × 10−5 | 0.045 |