Table 1 Variance in LOF SNV and indel burden explained by technical covariates

 C20X

1785.49

1

52.95

3.72e^-13

0.0056

 WGA

156.89

1

4.65

3.10e^-02

0.0005

 Center

716.08

2

10.61

2.48e^-05

0.0023

 BWA

79.59

5

0.47

7.97e^-01

0.0003

 RACE

30698.90

5

182.10

1.33e^-184

0.0973

 Residuals

281966.85

8363

0.8940

 C20X

52930.43

1

153.90

4.95e^-35

0.0072

 WGA

3744887.28

1

10888.62

0.0000

0.5080

 Center

383585.43

2

557.65

4.53e^-228

0.0520

 BWA

169507.9

5

98.57

2.76e^-101

0.0229

 RACE

146904.86

5

85.42

7.59e^-88

0.0199

 Residuals

2876257.21

8363

0.3900