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Table 2 Suggestive transcription factor enrichment of gene promoters more methylated in young cultures

From: Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS

Category

Term

Counta

Fold enrichmentb

FDRc

UCSC_TFBS

PAX5

288

1.32

4.35E-09

UCSC_TFBS

LMO2COM

297

1.31

6.04E-09

UCSC_TFBS

P53

321

1.25

2.23E-08

UCSC_TFBS

EGR3

111

1.77

5.34E-08

UCSC_TFBS

AP2

148

1.57

1.04E-07

UCSC_TFBS

NMYC

174

1.48

1.57E-07

UCSC_TFBS

ARNT

243

1.33

2.26E-07

UCSC_TFBS

NRSF

265

1.29

3.42E-07

UCSC_TFBS

MYCMAX

302

1.23

8.19E-07

UCSC_TFBS

NFKB

246

1.30

1.43E-06

UCSC_TFBS

AHRARNT

259

1.28

1.49E-06

UCSC_TFBS

CREB

218

1.33

1.79E-06

UCSC_TFBS

E47

290

1.23

2.99E-06

UCSC_TFBS

COUP

209

1.33

5.73E-06

UCSC_TFBS

TAXCREB

262

1.25

6.31E-06

  1. aNumber of inputted genes regulated by transcription factor listed
  2. bFold enrichment as measured by Fisher’s Exact Test
  3. cBenjamini-Hochberg False Discovery Rate