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Table 3 Suggestive transcription factor enrichment of gene promoters more methylated in old cultures

From: Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS

Category

Term

Counta

Fold enrichmentb

FDRc

UCSC_TFBS

PAX5

187

1.43

8.40E-10

UCSC_TFBS

SP1

95

1.73

1.66E-06

UCSC_TFBS

ATF

113

1.58

3.02E-06

UCSC_TFBS

NRSF

165

1.35

9.59E-06

UCSC_TFBS

MIF1

136

1.43

1.06E-05

UCSC_TFBS

P300

124

1.47

1.09E-05

UCSC_TFBS

ZID

150

1.38

1.14E-05

UCSC_TFBS

SREBP1

178

1.28

4.10E-05

UCSC_TFBS

MYOGNF1

145

1.35

6.27E-05

UCSC_TFBS

TAXCREB

162

1.30

8.37E-05

UCSC_TFBS

ZIC3

123

1.41

8.80E-05

UCSC_TFBS

MZF1

147

1.33

9.46E-05

UCSC_TFBS

AHRARNT

158

1.31

9.57E-05

UCSC_TFBS

HMX1

139

1.34

1.39E-04

UCSC_TFBS

TAL1BETAITF2

158

1.29

1.50E-04

  1. aNumber of inputted genes regulated by transcription factor listed
  2. bFold enrichment as measured by Fisher’s Exact Test
  3. cBenjamini-Hochberg False Discovery Rate