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Table 4 Conserved transcription factor enrichment of gene promoters more methylated in young cultures

From: Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS

Category

Term

Counta

Fold enrichmentb

FDRc

UCSC_TFBS

P300

49

1.67

0.007

UCSC_TFBS

TAL1BETAITF2

60

1.40

0.024

UCSC_TFBS

CDC5

52

1.46

0.027

UCSC_TFBS

ROAZ

52

1.44

0.027

UCSC_TFBS

P53

69

1.29

0.028

UCSC_TFBS

COUP

48

1.46

0.031

UCSC_TFBS

NFKB

56

1.42

0.032

UCSC_TFBS

EGR3

25

1.92

0.032

UCSC_TFBS

AP2

35

1.78

0.032

UCSC_TFBS

AP2GAMMA

18

2.19

0.040

  1. aNumber of inputted genes regulated by transcription factor listed
  2. bFold enrichment as measured by Fisher’s Exact Test
  3. cBenjamini-Hochberg False Discovery Rate
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BMC Genomics

ISSN: 1471-2164

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