Table 2 Affected KEGG pathways at the onset of European sea bass puberty
Pathway name | Genes involved |
|---|---|
Metabolic pathways | |
 - Nucleotide metabolism | nme3, pold3, cad, tyms, nt5e , dtymk |
 - Retinol metabolism | cyp26a1 |
 - Lipid metabolism | pnpla2 , gpd1, agrp2 , ptges |
 - Amino acid metabolism | odc1, pycr2, smox , ass1, cad, shmt1, pah |
Cellular processes | |
 - Cell cycle | bub3, mcm3, pcna, ttk, ccnd2, mad2l1bp, cdc28, aurkb, ndc80, spc25 |
 - Meiosis | mcm3, cdc28, dmc1, mad2l2, sycp2, syce1, cenph, cenpi, cenpf, ndc80, spc25 |
 - DNA replication and repair | mcm3, pold3, fen1, pcna, rfc3 |
 - Focal adhesion | actb , ccnd2, thbs1 |
Genetic information processing | |
 - FoxO signalling pathway | tgfbr1 , stat3 , plk4, ccnd2 |
 - Hippo signalling pathway | amh , tgfbr1 , ccnd2, actb |
 - Jak-STAT signalling pathway | stat3 , socs3 , ccnd2 |
 - TGF beta signalling pathway | amh , tgfbr1 , thbs1 |
 - MAPK signalling pathway | gpd1, cdc28, tgfbr1 |
 - TNF signalling pathway | socs3 |
 - Toll-like receptor signalling pathway | ctsk |
 - Wnt signalling pathway | cacybp, ccnd2 |
 - PI3K-Akt signalling pathway | ccnd2, thbs1 |
 - cAMP signalling pathway | adcyap1, amh |
 - Hedgehog signalling pathway | ccnd2, ihh |
 - Rap1 signalling pathway | actb, thbs1 |
Endocrine system | |
 - Prolactin signalling pathway | stat3 , socs3 , ccnd2 |
 - Renin secretion | aqp1 |
 - Thyroid hormone signalling pathway | actb |