De novo transcriptome analysis shows differential expression of genes in salivary glands of edible bird’s nest producing swiftlets

Table 4 Expression profiles of genes of potential importance in salivary gland development and EBN compositions

Gene function	Gene	AFM	AFC	AMC	AA
Salivary development	CREB3L2	65.608	76.666	51.669	0.000
	SEC63	36.723	34.793	50.081	5.926
	SEC24A	15.763	15.414	19.240	19.20
	SAR1	38.916	23.855	16.996	6.934
AA versus Aerodramus species
Gene function	Gene	AA	Aerodramus spp	log2	q-value
EGFR signalling pathway	ARF4	0.683	48.954	6.162	0.026
	BCAR1	6.407	51.836	3.016	0.003
	CAV1	0.695	50.207	6.174	0.026
	CEBPA	8.626	49.820	2.529	0.018
	ELF3	6.816	603.607	6.468	0.001
	EPS15	0.198	10.035	5.657	0.026
	EPS8	0.754	13.668	4.178	0.026
	JUN	0.411	11.504	4.803	0.021
	PLEC	6.047	31.197	2.367	0.005
	RAB5A	17.934	47.435	1.403	0.046
	REPS1	6.795	21.529	1.663	0.040
	ZPR1	1.079	13.242	3.617	0.001
	VAV2	49.553	239.912	2.275	0.011
	STAT3	2.453	53.308	4.441	0.001
N-glycan biosynthesis	ALG2	6.546	90.860	3.794	0.001
	MGAT1	4.617	91.067	4.301	0.004
	RPN1	66.407	552.366	3.056	0.003
	FUT8	13.173	84.076	2.674	0.003
	RPN2	1.069	71.026	6.053	0.001
AMC versus AFC
Gene function	Gene	AMC	AFC	log2	q-value
EGFR signalling pathway	JUND	4.911	39.541	3.009	0.001
	HDAC	1.357	580.771	8.740	0.001
	BCAR	7.776	200.736	4.690	0.001
N-glycan biosynthesis	MGAT	20.278	256.555	3.661	0.046
Alanine and Aspartate metabolism	GOT1	226.741	7.0263	−5.012	0.000
Alanine and Aspartate metabolism	PDHB	894.023	135.641	−2.721	0.000
AFM versus AFC
Gene function	Gene	AFM	AFC	log2	q-value
MAPK signalling pathway	HMGN1	23,486.800	2685.98	−3.128	0.001
BMP signalling pathway	TOB2	20.463	0.959	−4.414	0.001
Fatty acid synthesis	ACADVL	10.909	50.803	2.219	0.001
Gender comparison of AFC
Gene function	Gene	Male	Female	log2	q-value
N-glycan trimming	EDEM2	3.951	0.359	3.459	0.008

ISSN: 1471-2164