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Table 4 Expression profiles of genes of potential importance in salivary gland development and EBN compositions

From: De novo transcriptome analysis shows differential expression of genes in salivary glands of edible bird’s nest producing swiftlets

Gene function

Gene

AFM

AFC

AMC

AA

Salivary development

CREB3L2

65.608

76.666

51.669

0.000

SEC63

36.723

34.793

50.081

5.926

SEC24A

15.763

15.414

19.240

19.20

SAR1

38.916

23.855

16.996

6.934

AA versus Aerodramus species

Gene function

Gene

AA

Aerodramus spp

log2

q-value

EGFR signalling pathway

ARF4

0.683

48.954

6.162

0.026

BCAR1

6.407

51.836

3.016

0.003

CAV1

0.695

50.207

6.174

0.026

CEBPA

8.626

49.820

2.529

0.018

ELF3

6.816

603.607

6.468

0.001

EPS15

0.198

10.035

5.657

0.026

EPS8

0.754

13.668

4.178

0.026

JUN

0.411

11.504

4.803

0.021

PLEC

6.047

31.197

2.367

0.005

RAB5A

17.934

47.435

1.403

0.046

REPS1

6.795

21.529

1.663

0.040

ZPR1

1.079

13.242

3.617

0.001

VAV2

49.553

239.912

2.275

0.011

STAT3

2.453

53.308

4.441

0.001

N-glycan biosynthesis

ALG2

6.546

90.860

3.794

0.001

MGAT1

4.617

91.067

4.301

0.004

RPN1

66.407

552.366

3.056

0.003

FUT8

13.173

84.076

2.674

0.003

RPN2

1.069

71.026

6.053

0.001

AMC versus AFC

Gene function

Gene

AMC

AFC

log2

q-value

EGFR signalling pathway

JUND

4.911

39.541

3.009

0.001

HDAC

1.357

580.771

8.740

0.001

BCAR

7.776

200.736

4.690

0.001

N-glycan biosynthesis

MGAT

20.278

256.555

3.661

0.046

Alanine and Aspartate metabolism

GOT1

226.741

7.0263

−5.012

0.000

PDHB

894.023

135.641

−2.721

0.000

AFM versus AFC

Gene function

Gene

AFM

AFC

log2

q-value

MAPK signalling pathway

HMGN1

23,486.800

2685.98

−3.128

0.001

BMP signalling pathway

TOB2

20.463

0.959

−4.414

0.001

Fatty acid synthesis

ACADVL

10.909

50.803

2.219

0.001

Gender comparison of AFC

Gene function

Gene

Male

Female

log2

q-value

N-glycan trimming

EDEM2

3.951

0.359

3.459

0.008

  1. AFC Aerodramus fuciphagus from cave
  2. AFM Aerodramus fuciphagus from man-made house
  3. AMC Aerodramus maximus from cave
  4. AA Apus affinis