Fig. 3
From: Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice
Mitochondrial, Redox and Metabolic Transcriptional Signature: DEGs obtained from cardiac RNA sequencing (RNAseq) partitioned into the following biological categories using Gene Ontology and Reactome pathway designations; (a) Mitochondrial Genome and Function, (b) Oxidoreductase Activity, and (c) Amino Acid Metabolism and Bioenergetics. Log2 fold change (Log2FC) derived by RNAseq is provided for each gene along with an adjusted p-value to account for false discovery rate (q-value). d Real-time quantitative PCR validation (n = 4–6/group) of 6 genes representing each major biological pathway. *p < 0.05, **p < 0.01, ***p < 0.001