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Fig. 2 | BMC Genomics

Fig. 2

From: Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible

Fig. 2

Agreement between RepProfile and clone validation. a Fraction of editing predicted by clones vs fraction predicted by RepProfile. RepProfile and clones show good agreement in the rdgA FB4_DM element. b RNA-editing predictions aligned to RNA secondary structure as predicted by RNAstructure [39, 40]. Positions are colored so that aligned pairs are the same color. Unpaired positions are not colored. Both methods predict hyper-editing only in the helical portion of this repeat, consistent with the fact that ADAR is a dsRNA binding protein. c Explanation of RNA structure coloring. A gradient from red to green to blue is stretched across the length of the sequence. Paired positions are colored according to the minimum of their position and the position they are paired to. Unpaired position are not colored

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