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Table 2 Metabolic components of the biomass function

From: Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance

Complex metabolites • protein, composed of:
 ◦ tRNA ligated amino acids (20)*
• lipid, composed of
 ◦ sphingomyelin*
 ◦ cholesterol
 ◦ phosphatidyl choline
 ◦ phosphatidyl ethanoloamine
 ◦ triacylglycerides*
 ◦ diacyclglycerides*
 ◦ phosphatidyl inositol*
 ◦ phosphatidyl glycerol*
 ◦ acyl phosphatidyl glycerol*
• reduced and oxidized glutathione*
• protoheme
Amino Acids • alanine • arginine
• asparagine • aspartate
• cysteine • glutamate
• glutamine • glycine
• histidine • isoleucine
• leucine • lysine
• methionine • serine
• phenylalanine • proline
• threonine • tryptophan
• tyrosine • valine
Carbohydrates • malate*
• α-ketoglutarate*
Nucleotides • ATP • dATP
• CTP • dCTP
• GTP • dGTP
• UTP • dTTP
• thiamine diphosphate
Excreted metabolites • lactate*
• hemozoin*
Vitamins • pyridoxal
• 5-phosphate riboflavin
Other • s-adenosyl l-methionine • putrescine
• spermidine • 2-octaprenyl 6-hydroyphenol
• f-thf • mthf
• thf • FAD
• coenzyme-A • NAD
• water • Fe2+ & Fe3+
• NADP • SO4
• NH4+
  1. f-thf = formyl tetrahydrofolate; mthf = methyltetrahydrofolate; thf = tetrahydrofolate
  2. *metabolites that have been added to the iPfal17 and are not present in the biomass function of iTH266