Table 6 Essential reactions unique to sensitive parasites

2_7_8_3

CDP-choline[c] + ceramide[c] + h[c] = > CMP[c] + sphingomyelin[c]

2.7.8.3

sphingomyelinase 2 in lipid metabolism

PFF1210w^a

PFF1215w

AMETt2

adenosyl methionine[e] + h[e] = > adenosyl methionine[c] + h[c]

-

adenosyl methionine import

PF11_0334

PFB0435c^a

PFE0775c^a

PFF1430c

PFL0420w

PFL1515c^a

EX_o2(e)

O₂[e] < =>

-

oxygen exchange

-

EX_ptrc(e)

putrescine[e] < =>

-

putrescine exchange

-

GAT_c

diacylglycerol[c] + acyl-coenzyme-A[c] = > coenzyme-A[c] + triacylglycerol[c]

2.3.1.20

diacylglycerol O-acyltransferase in lipid metabolism

PFC0995c

GPDDA4

glycerophosphoglycerol [c] + H₂O [c] = > glycerol 3-phosphate[c] + glycerol[c] + h[c]

3.1.4.46

glycerophosphodiester phosphodiesterase in lipid metabolism and glycolysis

PF14_0060

O2t

O₂[e] < => O₂[c]

-

oxygen import

-

O2tmt

O₂[m] < => O₂[c]

-

oxygen transport into mitochondria

-

PItap

phosphate[ap] < => phosphate[c]

-

phosphate transport into apicoplast

-

PTRCt2

h[e] + putrescine[e] = > h[c] + putrescine[c]

-

putrescine import

-

PYK

ADP [c] + h[c] + phosphoenol pyruvate[c] = > ATP[c] + pyruvate[c]

2.7.1.40

pyruvate kinase in glycolysis

PFF1300w

amet_ex

adenosyl methionine[e] < =>

-

adenosyl methionine exchange

-