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Table 3 Gene ontology term annotation of male Cluster 9 and female Cluster 3. Italics indicate GO terms that are significant in both clusters. BP: Biological process; CC: Cellular component; MF: Molecular function. Benjamini-corrected p-value

From: Relating past and present diet to phenotypic and transcriptomic variation in the fruit fly

Cluster

Category

GO ID

Term

P-value

C9

Male

BP

GO:0006396

RNA processing

<0.001

BP

GO:0034660

ncRNA metabolic process

<0.001

BP

GO:0034470

ncRNA processing

<0.001

MF

GO:0000166

nucleotide binding

<0.001

CC

GO:0031981

nuclear lumen

<0.001

MF

GO:0001882

nucleoside binding

<0.001

BP

GO:0016071

mRNA metabolic process

<0.001

MF

GO:0005524

ATP binding

<0.001

MF

GO:0032559

adenyl ribonucleotide binding

<0.001

BP

GO:0006397

mRNA processing

<0.001

MF

GO:0030554

adenyl nucleotide binding

<0.001

MF

GO:0001883

purine nucleoside binding

<0.001

BP

GO:0006399

tRNA metabolic process

<0.001

CC

GO:0070013

intracellular organelle lumen

<0.001

CC

GO:0043233

organelle lumen

<0.001

CC

GO:0031974

membrane-enclosed lumen

<0.001

MF

GO:0017076

purine nucleotide binding

<0.001

MF

GO:0032553

ribonucleotide binding

<0.001

MF

GO:0032555

purine ribonucleotide binding

<0.001

BP

GO:0022613

ribonucleoprotein complex biogenesis

0.002

MF

GO:0003723

RNA binding

<0.001

BP

GO:0008380

RNA splicing

0.004

BP

GO:0042254

ribosome biogenesis

0.004

MF

GO:0004386

helicase activity

0.001

CC

GO:0005730

nucleolus

0.003

MF

GO:0008186

RNA-dependent ATPase activity

0.003

MF

GO:0004004

ATP-dependent RNA helicase activity

0.003

BP

GO:0006364

rRNA processing

0.012

BP

GO:0016072

rRNA metabolic process

0.012

BP

GO:0006360

transcription from RNA polymerase I promoter

0.021

CC

GO:0005654

nucleoplasm

0.011

BP

GO:0006418

tRNA aminoacylation for protein translation

0.022

BP

GO:0043039

tRNA aminoacylation

0.022

MF

GO:0016875

ligase activity, forming carbon-oxygen bonds

0.007

MF

GO:0016876

ligase activity, forming aminoacyl-tRNA

0.007

MF

GO:0004812

aminoacyl-tRNA ligase activity

0.007

BP

GO:0043038

amino acid activation

0.023

MF

GO:0016779

nucleotidyltransferase activity

0.007

MF

GO:0034062

RNA polymerase activity

0.006

MF

GO:0003899

DNA-directed RNA polymerase activity

0.006

MF

GO:0003724

RNA helicase activity

0.006

BP

GO:0035196

gene silencing by miRNA, production of miRNAs

0.026

BP

GO:0035195

gene silencing by miRNA

0.028

MF

GO:0008026

ATP-dependent helicase activity

0.013

MF

GO:0070035

purine NTP-dependent helicase activity

0.013

BP

GO:0000398

nuclear mRNA splicing, via spliceosome

0.047

BP

GO:0000377

RNA splicing, via transesterification reactions with

0.047

BP

GO:0000375

RNA splicing, via transesterification reactions

0.047

MF

GO:0003729

mRNA binding

0.015

MF

GO:0042624

ATPase activity, uncoupled

0.018

MF

GO:0004540

ribonuclease activity

0.021

MF

GO:0032549

ribonucleoside binding

0.029

MF

GO:0003677

DNA binding

0.031

MF

GO:0000287

magnesium ion binding

0.038

MF

GO:0016887

ATPase activity

0.040

C3

Female

BP

GO:0009451

RNA modification

0.002

CC

GO:0030529

ribonucleoprotein complex

0.001

BP

GO:0034660

ncRNA metabolic process

0.004

BP

GO:0034470

ncRNA processing

0.003

BP

GO:0042254

ribosome biogenesis

0.006

BP

GO:0022613

ribonucleoprotein complex biogenesis

0.027

CC

GO:0022625

cytosolic large ribosomal subunit

0.020