Characterization of the peripheral blood transcriptome and adaptive evolution of the MHC I and TLR gene families in the wolf (Canis lupus)

Table 2 Immune-related pathways identified in the wolf blood transcriptome

KO identifier	Pathway name	Annotated unigenes	Mapped genes	Genes in pathway
ko04062	Chemokine signaling pathway	216	114	146
ko04660	T cell receptor signaling pathway	166	77	85
ko04670	Leukocyte transendothelial migration	155	60	75
ko04620	Toll-like receptor signaling pathway	136	67	76
ko04650	Natural killer cell mediated cytotoxicity	132	66	81
ko04666	Fc gamma R-mediated phagocytosis	121	50	58
ko04640	Hematopoietic cell lineage	98	63	77
ko04621	NOD-like receptor signaling pathway	93	39	51
ko04662	B cell receptor signaling pathway	92	52	57
ko04612	Antigen processing and presentation	91	36	41
ko04664	Fc epsilon RI signaling pathway	87	39	45
ko04622	RIG-I-like receptor signaling pathway	79	46	53
ko04610	Complement and coagulation cascades	75	50	78
ko04623	Cytosolic DNA-sensing pathway	62	41	51
ko04672	Intestinal immune network for IgA production	59	28	37

ISSN: 1471-2164