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Table 1 Transcriptomic and proteomic analysis of the overlapped genes and their corresponding proteins in HBV (+) mouse

From: Proteomic and transcriptomic studies of HBV-associated liver fibrosis of an AAV-HBV-infected mouse model

  Fold Change  
Transcriptomic Proteomic protein
Gnen ID Location 1 M 3 M 6 M 1 M 3 M 6 M Function Protein
ENSMUSG
00000038155
cytoplam; 4.70 8.8 8.27 N up N dinitrosyl-iron complex binding; glutathione peroxidase activity; glutathione transferase activity; S-nitrosoglutathione binding Gstp2
ENSMUSG
00000034456
cytosol N −2.55 −2.70 N N down urocanatehydratase activity Uroc1
ENSMUSG
00000074768
cytosol, extracellular N −8.56 −6.96 N up N zinc ion binding, S-adenosylmethionine-homocysteine S-methyltransferase activity Bhmt
ENSMUSG
00000039206
lysosome N −2.91 −2.65 N N up metal ion binding, acylglycerol lipase activity Daglb
ENSMUSG
00000026385
endoplasmic reticulum, extracellular N −3.00 −2.46 N N down lipid binding Dbi
ENSMUSG
00000033712
nuclear chromatin N −2.82 −3.30 N N down RNA polymerase II core binding, enzyme inhibitor activity Ccar2
ENSMUSG
00000032235
nucleus, N −2.46 −2.81 N N down protein binding Ice2
ENSMUSG
00000025950
cytosol, extracellular, peroxisome N −2.57 −2.05 N N down isocitrate dehydrogenase (NADP+) activity Idh1
ENSMUSG
00000031173
Mitochondrion N −3.42 −3.08 down N N ornithine carbamoyltransferase activity Otc
ENSMUSG
00000041268
extracellular N −2.80 −2.62 down N N RabGTPase binding Dmxl2
ENSMUSG
00000027187
cytosol, extracellular, peroxisome N −2.28 −2.00 N down N antioxidant activity Cat
ENSMUSG
00000046441
Nucleus. Cytoplasm. N −3.36 −3.90 N N down mRNA (nucleoside-2-O-)-methyltransferase activity Cmtr2
ENSMUSG
00000036591
cytoskeleton, golgi apparatus N −2.63 −3.54 N N down GTPase activator activity Arhgap21
ENSMUSG
00000021277
cytosol, mitochondrion N −2.81 −2.60 N N down protein binding, tumor necrosis factor receptor binding Traf3
ENSMUSG
00000030934
mitochondrion N −2.09 −3.03 N down N ornithine-oxo-acid transaminase activity Oat
ENSMUSG
00000055204
nucleus N 4.41 3.712 N up up chromatin binding Ankrd17
ENSMUSG
00000071657
endoplasmic reticulum N 2.88 3.53 N N up protein binding Bscl2
ENSMUSG
00000070390
cytosol, nucleus N 8.16 5.02 N N up protein binding Nlrp1b
ENSMUSG
00000001674
nucleus N 3.94 3.10 N N up ATP binding, protein binding Ddx18
ENSMUSG
00000040466
cytosol, extracellular, nucleus N 2.35 3.03 N N up biliverdinreductase activity, riboflavin reductase (NADPH) activity Blvrb
ENSMUSG
00000020844
cytosol, nucleus N 4.28 2.74 N up N thioredoxin-disulfide reductase activity Nxn
ENSMUSG
00000028163
cytosol, mitochondrion, nucleus N 2.99 2.22 N down N DNA binding Nfkb1
ENSMUSG
00000024613
nucleus N 6.15 5.93 N up N skeletal system development Tcof1
ENSMUSG
00000040940
cytosol,plasma membrane N 2.87 2.24 N N down protein binding, GTPase activator activity Arhgef1
ENSMUSG
00000027840
extracellular N 13.99 7.21 N N up protein binding wnt2b
ENSMUSG
00000055884
nucleus 5.70 N −2.35 up N N chromatin binding Fancm
ENSMUSG
00000060803
Cytoplasm. Mitochondrion N N −8.02 down down down JUN kinase binding Gstp1
ENSMUSG
00000041324
extracellular N N 4.30 N up N cytokine activity Inhba
  1. N: no difference
  2. up: up-regulated expression, compared with HBV(−) mouse
  3. down: down-regulated expression, compared with HBV(−) mouse