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Table 1 Summary of the findings and data sets searched in this study

From: Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets

Data set

Size (nt)

Sequences

Median seq. Length

Number of qnr fragmentsa

Assembled qnr sequences >200 aab

Metagenomic

Previously known

Putatively novel

Human microbiomes [43]

3.69 × 1012

3.90 × 1010

93

83,485

(2.14 × 10−6)

1

0

Human intestinal tract [34]

3.71 × 1011

5.22 × 109

75

12,966

(2.49 × 10−6)

0

0

Human intestinal tract [53]

7.10 × 1010

4.41 × 108

148

264

(5.99 × 10−7)

1

0

Waste water treatment plant [54]

4.82 × 1011

5.18 × 109

101

19,458

(3.76 × 10−6)

4

2

Antibiotic-polluted Indian lake [55]

6.75 × 109

6.68 × 107

101

57,415

(8.59 × 10−4)

5

0

Antibiotic-polluted Indian soil [35]

4.73 × 1010

4.68 × 108

101

840

(1.80 × 10−6)

0

0

Antibiotic-polluted Indian river sediment [56]

3.89 × 1010

3.85 × 108

101

67,021

(1.74 × 10−4)

4

1

Indian well water [35]

7.32 × 1010

7.25 × 108

101

1704

(2.35 × 10−6)

3

0

Oil spill [57]

2.75 × 1011

2.72 × 109

101

12,533

(4.60 × 10−6)

0

3

Pune river sediments [58]

3.9 × 1011

3.11 × 109

126

4805

(1.55 × 10−6)

5

4

Wadden sea [59]

8.4 × 109

5.23 × 107

161

723

(1.38 × 10−5)

0

5

Tara oceans [60]

7.20 × 1012

7.25 × 1010

101

100,795

(1.39 × 10−6)

2

5

Other

 NCBI nt

5.22 × 1010

2.07 × 107

740

709

(3.42 × 10−5)

466

42

 NCBI RefSeq bacterial

9.63 × 109

5.24 × 103

1,176,248

54

(1.03 × 10−2)

49

2

 NCBI env_nt

9.55 × 109

2.07 × 107

117

71

(3.43 × 10−6)

3

4

 Totals:

1.27 × 1013

1.30 × 1011

N/A

362,843

(2.79 × 10−6)

611

72

  1. aRelative abundance given in parenthesisbBoth putatively novel and previously known sequences are included in this listing