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Table 1 Summary of the findings and data sets searched in this study

From: Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets

Data set Size (nt) Sequences Median seq. Length Number of qnr fragmentsa Assembled qnr sequences >200 aab
Metagenomic Previously known Putatively novel
Human microbiomes [43] 3.69 × 1012 3.90 × 1010 93 83,485 (2.14 × 10−6) 1 0
Human intestinal tract [34] 3.71 × 1011 5.22 × 109 75 12,966 (2.49 × 10−6) 0 0
Human intestinal tract [53] 7.10 × 1010 4.41 × 108 148 264 (5.99 × 10−7) 1 0
Waste water treatment plant [54] 4.82 × 1011 5.18 × 109 101 19,458 (3.76 × 10−6) 4 2
Antibiotic-polluted Indian lake [55] 6.75 × 109 6.68 × 107 101 57,415 (8.59 × 10−4) 5 0
Antibiotic-polluted Indian soil [35] 4.73 × 1010 4.68 × 108 101 840 (1.80 × 10−6) 0 0
Antibiotic-polluted Indian river sediment [56] 3.89 × 1010 3.85 × 108 101 67,021 (1.74 × 10−4) 4 1
Indian well water [35] 7.32 × 1010 7.25 × 108 101 1704 (2.35 × 10−6) 3 0
Oil spill [57] 2.75 × 1011 2.72 × 109 101 12,533 (4.60 × 10−6) 0 3
Pune river sediments [58] 3.9 × 1011 3.11 × 109 126 4805 (1.55 × 10−6) 5 4
Wadden sea [59] 8.4 × 109 5.23 × 107 161 723 (1.38 × 10−5) 0 5
Tara oceans [60] 7.20 × 1012 7.25 × 1010 101 100,795 (1.39 × 10−6) 2 5
Other
 NCBI nt 5.22 × 1010 2.07 × 107 740 709 (3.42 × 10−5) 466 42
 NCBI RefSeq bacterial 9.63 × 109 5.24 × 103 1,176,248 54 (1.03 × 10−2) 49 2
 NCBI env_nt 9.55 × 109 2.07 × 107 117 71 (3.43 × 10−6) 3 4
 Totals: 1.27 × 1013 1.30 × 1011 N/A 362,843 (2.79 × 10−6) 611 72
  1. aRelative abundance given in parenthesisbBoth putatively novel and previously known sequences are included in this listing